Károly Zsolnai-Fehér interviews Pushmeet Kohli about AlphaGenome, an AI system that predicts how DNA sequences affect molecular processes. They discuss long sequence inputs, regulatory regions, gene expression and splicing, explaining why interpreting genetic changes requires more than reading protein-coding genes.
Károly Zsolnai-Fehér and Pushmeet Kohli examine the model's reported evaluations and an atlas of predicted variants. These are research predictions, not diagnoses or proven treatments: biological experiments and causal understanding remain essential to testing what the system suggests.
Károly Zsolnai-Fehér and Pushmeet Kohli consider how AI could support virtual cells and scientific discovery beyond genomics. Future disease, materials and climate applications are presented as ambitions, while generated fluid simulations illustrate concepts rather than guaranteeing physically accurate simulation.
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